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Standard minimal inhibitory concentrations (MIC) assays (27) were conducted to determine sensitivity to each chemical, and appropriate concentrations chosen for the remaining experiments

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Conversely, breast cancer cells produce IL-6, which activates the JAK2/STAT3 axis, inducing TAMs to secrete TGF-1, thereby forming a positive feedback loop that ultimately facilitates malignant tumor progression [121]

10.1038/ni1254 43 HeK.WangZ